Blood Serology

Confidential Syphilis Testing in Kathmandu

Accurate blood testing for Treponema pallidum. We offer complete diagnostic pathways: rapid screening (VDRL/RPR) to detect active inflammation, TPHA for absolute confirmation, and quantitative Titer testing to monitor treatment success.

VDRL / RPR

Initial non-treponemal screening for active infections.

Rs 500

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VDRL in Titer

Measures antibody concentration to track treatment progress.

Rs 800

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Confirmatory

TPHA Screen

Highly specific treponemal test to confirm a positive VDRL.

Rs 800

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TPHA in Titer

Advanced quantitative confirmation for complex cases.

Rs 1,000

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* Turnaround Time: Same Day for Lab Visits.

Understanding Syphilis Infection

Syphilis is a highly contagious bacterial infection caused by Treponema pallidum. It is primarily spread through sexual contact. The disease develops in stages, and symptoms can vary or even disappear entirely, making laboratory testing the only reliable way to confirm an infection. If left untreated, it can cause severe, irreversible damage to the heart, brain, and nervous system.

Highly Curable: When diagnosed early via VDRL/TPHA blood tests, Syphilis is completely curable with a straightforward course of antibiotics (typically Penicillin).

Testing Window Period

Syphilis antibodies take time to develop. Testing too early can result in a false negative.

Standard Window:

3 to 6 weeks post-exposure. If a painless sore (chancre) appears, testing is highly recommended immediately.

The Stages & Symptoms

Symptoms depend heavily on the stage of the infection:

Primary Stage: A single, painless sore (chancre) where the bacteria entered. Often goes unnoticed.
Secondary Stage: Non-itchy skin rash (often on palms/soles), swollen lymph nodes, fever.
Latent Stage: No visible symptoms, but the infection remains active in the blood.

Sample Requirement

Quick, routine venous blood collection.

Blood Specimen

A certified phlebotomist collects a standard blood sample. VDRL and TPHA are both performed using separated serum.

No Fasting Required

Food or beverage consumption does not alter Treponema antibodies. You can visit our Basundhara lab at any time.

Medical Consultation

Clinical Care at Derma Clinic

Syphilis is completely curable in its early stages with targeted antibiotics (such as Penicillin injections). If your VDRL or TPHA result is positive, consult directly with the specialist venereologists at Derma Clinic (located in the same building) for immediate, confidential treatment.

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Frequently Asked Questions

What is the difference between VDRL and TPHA?

VDRL (or RPR) is a highly sensitive screening test that detects non-specific antibodies indicating an active infection or inflammation. TPHA is a highly specific confirmatory test that detects antibodies directly against the Syphilis bacteria (Treponema pallidum).

What is the window period for a Syphilis test?

It takes about 3 to 6 weeks after exposure for Syphilis antibodies to reach detectable levels in your blood.

Why do I need a Titer test?

A titer test measures the exact amount (concentration) of antibodies in your blood. This is crucial for doctors to monitor if your Syphilis treatment (antibiotics) is working effectively, as the titer levels should drop significantly after successful treatment.